1st, get
ClamXav. It's donation ware, and is a good enough anti-virus that Apple used it for their server version of MacOS X. Check your system with it, especially your user files.
2nd, get
LittleSnitch. It checks for outgoing calls, and allows you to validate (or not) anything it does not recognize. If you have a Trojan Horse sending data to something you don't care to allow, LittleSnitch will alert you.
3rd, if you can, upgrade to Lion. Apple has quietly introduced a hidden utility that tracks and destroys certain Trojan Horses, and attempts to keep it updated, behind the scenes, to keep up with the malware developers.